Kian84 is notorious for being Mr. Unmotivated, or in other words, living his life as if he has no other reason besides the fact that he was born. He ends up setting off on a trip to the Amazon which he has wanted to do for a while. However, he has no other plans other than the beginning and end points of his journey. With a single backpack for his entire trip, he must survive in the Amazon.

Kian84 and Lee Si Eon set off on a fishing tour on the Amazon river and attempt to catch piranhas. Their tour guide invites them to stay at his family home, and Kian84 and Si Eon get a taste of the local cuisine. Some of it suits their tastes, but some foods are an absolute culture shock. Meanwhile, Kian84 and Si Eon head to their second destination in Peru.

Kian84 and Si Eon wake up in Cusco and decide to tour the city. However, as they keep spending time together, they realize their personalities and travel styles tend to clash. Just in time to ease the tension, Pani Bottle shows up and joins the trip. The three rent motorcycles and go on a journey to their next destination together.

The trio of accidental travelers head to La Raya observatory. As they continue to ride on their motorcycles, they come across some treasures. They get to relax at a hot spring they come across by chance and enjoy the beautiful scenery until finally arriving at their destination. However, their biggest challenge proves to be altitude sickness.

The trio heads to La Paz, Bolivia, the city that boasts the highest altitude of all capital cities in the world. Although they are mesmerized by the unique and beautiful view, they soon face a terrible traffic jam that leaves their bus stuck on the road. Later on, Kian84 goes to meet a local friend who lives beyond the aptly named Death Road.

Kian84 gets to fulfill his wish of meeting a local friend on his South American trip. Porfi, who is the same age as Kian84, shows up out of nowhere on a zipline in the mountains. He takes Kian84 to his house, but the journey takes much longer than expected. As they share each other's life stories, the two friends grow closer. Meanwhile, Pani Bottle and Si Eon go camping together where they meet their own set of adventures.

Kian84 spends one last afternoon with his friend Porfi and his son, Porfi Junior. They head to a small town called Coroico where he goes on a shopping spree to buy Porfi Junior anything he wants. Later, Kian84, Si Eon, and Pani Bottle head to their final destination, the Uyuni Salt Flats. Taking a bus for nine hours from La Paz, they finally arrive at the largest mirror in the world.

A new adventure begins on the Tea Horse Road! Kian84 sets off before the other members to arrive in Nepal. His adventure begins in the highlands, where he experiences the life of a Sherpa by carrying loads through the mountains and valleys. He also meets villagers on the way and befriends them.

After Kian84 is done experiencing life as a Sherpa in the Himalayas, he reunites with Dex, Si Eon, and Pani Bottle. The four head to Pokhara and look for places to grab dinner. The next day, they entertain themselves at an amusement park, which to their surprise, is run manually.

The Four Brothers arrive at the Gurkha Academy. Along with students who strive to become Gurkhas, they challenge themselves with tough physical exercise. Afterward, they take English and math classes and make friends along the way. Will they be able to survive the tough Gurkha preparation?

After deciding to spend the night at the Gurkha Academy, the Four Brothers run the doko race. While they must run 3km with a heavy load on their backs, they are determined not to stop. Afterward, they head to Tangting, a Gurung village where they plan to camp the night.

The Four Brothers camp in Tangting and prepare Korean food with the little ingredients they have. Afterward, they head to Kathmandu where they find a luxurious lodging with a swimming pool and take a group photo in traditional Nepali clothes before Dex's departure.

While Dex returns to Korea, the remaining three take a flight to China where they will explore the night market and the Tea Horse Road and meet minority groups. Kian84 is desperate to meet the Nakhi people while Si Eon prepares a surprise for his two younger brothers.

After renting a car, the Three Brothers finally reach a Nakhi village. They meet Nakhi sisters who are happy to give them a tour around the village and help them meet the Dongba. Afterward, the Three Brothers help out with the farm work and get ready to set off to their last destination of the trip.

The final day of the brothers' adventure has finally come. Kian84 prepares to check an item off his bucket list by doing the 5-point prostration, and the Three Brothers prepare themselves for this final activity. At last, they wrap up the show by sharing their remarks and reflecting on it.